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Eco-friendly Oxidative Iodination of Various Arenes with a Urea-Hydrogen Peroxide Adduct (UHP) as the Oxidant

Piotr Lulinski, Anna Kryska, Maciej Sosnowski, Lech Skulski*

*Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, 02-097 Warsaw, Poland, Email:

P. Lulinski, A. Kryska, M. Sosnowski, L. Skulski, Synthesis, 2004, 441-445.

DOI: 10.1055/s-2004-815955


Eco-friendly laboratory procedures allow the oxidative iodination of various activated and deactivated arenes with molecular iodine, in the presence of UHP (percarbamide), a stable, strongly H-bonded, solid urea-hydrogen peroxide adduct as the oxidant.

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Key Words

iodoarenes, arenes, halogenation, iodine, peroxides, urea-hydrogen peroxide adduct

ID: J66-Y2004-1960