MgI₂ as an Additive in Ir(I)-Catalyzed Addition of Silylacetylenes to Imines: Expeditious Synthesis of Propargylic Amines

Christian Fischer, Erick M. Carreira*

*Laboratorium für Organische Chemie, ETH Hönggerberg, 8093 Zürich, Switzerland, Email: Carreiraorg.chem.ethz.ch

C. Fischer, E. M. Carreira, Synthesis, 2004, 1497-1503.

DOI: 10.1055/s-2004-822403

---

Abstract

MgI₂ as an additive enables a dramatic improvement in the [IrCl(COD)]₂-catalyzed addition reaction of silylacetylenes and imines. This general and convenient reaction provides various amine products in excellent yields and can be conducted in THF as well as in the absence of solvent.

see article for more examples

see article for more reactions

---

---

Key Words

Propargylamines

---

ID: J66-Y2004-2110