MgI2 as an Additive in Ir(I)-Catalyzed Addition of Silylacetylenes to Imines: Expeditious Synthesis of Propargylic Amines
Christian Fischer, Erick M. Carreira*
*Laboratorium für Organische Chemie, ETH Hönggerberg, 8093 Zürich,
Switzerland, Email: Carreira
org.chem.ethz.ch
C. Fischer, E. M. Carreira, Synthesis, 2004, 1497-1503.
Abstract
MgI2 as an additive enables a dramatic improvement in the [IrCl(COD)]2-catalyzed addition reaction of silylacetylenes and imines. This general and convenient reaction provides various amine products in excellent yields and can be conducted in THF as well as in the absence of solvent.
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Key Words
ID: J66-Y2004-2110
