IBX/n-Bu4NBr/CH2Cl2-H2O: a new mild system for selective oxidation of secondary alcohols
Chutima Kuhakarn*, Krisada Kittigowittana, Manat Pohmakotr and Vichai Reutrakul
*Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand, Email: scckkmahidol.ac.th
C. Kuhakarn, K. Kittigowittana, M. Pohmakotr, V. Reutrakul, Tetrahedron, 2005, 61, 8995-9000.
A chemoselective oxidation of secondary alcohols with IBX/n-Bu4NBr in CH2Cl2-H2O gave ketones in good yields and allowed the oxidation of secondary hydroxyl group even in the presence of primary hydroxyl groups.
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