Phosphorodiamidic Acid as a Novel Structural Motif of Brønsted Acid Catalysts for Direct Mannich Reaction of N-Acyl Imines with 1,3-Dicarbonyl Compounds
Masahiro Terada*, Keiichi Sorimachi, Daisuke Uraguchi
*Department of Chemistry, Graduate School of Science, Tohoku University,
Aoba-ku, Sendai 980-8578, Japan, Email: mterada
mail.tains.tohoku.ac.jp
M. Terada, K. Sorimachi, D. Uraguchi, Synlett, 2006, 133-136.
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Abstract
Achiral and chiral phosphorodiamidic acids were developed as efficient Brønsted acid catalysts for the direct Mannich reaction of N-acyl imines with 1,3-dicarbonyl compounds.
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Key Words
organocatalysis, Mannich reaction, active methylene compounds, green chemistry, asymmetric catalysis, imines
ID: J60-Y2006-4190
