Reactions of alkyl (halomethyl)furancarboxylates with hexamethylenetetramine
I. M. Lapina, L. M. Pevzner and A. A. Potekhin
St. Petersburg State University, Universitetskii pr. 26, St. Petersburg, 198504, Russia
I. M. Lapina, L. M. Pevzner, A. A. Potekhin, Russ. J. Gen. Chem., 2006, 1304-1309.
All isomers of (aminomethyl)furancarboxylic acids were prepared by the Delepine reaction from alkyl (halomethyl)furancarboxylates. Treatment of the initially formed quaternary salt with an ethanolic HCl solution gave the salts of the corresponding unstable amino acid esters. Hydrolysis of the crude esters yielded stable amino acid salts.
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