Nitroaldol Reaction in Aqueous Media: An Important Improvement of the Henry Reaction
Roberto Ballini* and Giovanna Bosica
*Dipartimento di Scienze Chimiche dell'Università, Via S. Agostino n. 1,
62032 Camerino, Italy, Email: roberto.ballini
unicam.it
R. Ballini, G. Bosica, J. Org. Chem., 1997, 62, 425-427.
DOI: 10.1021/jo961201h
Abstract
The Henry reaction can be performed under very mild reaction conditions in 0.025 M NaOH in the presence of cetyltrimethylammonium chloride as cationic surfactant. Short reaction times are required and both primary and secondary nitroalkanes give good results.
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Key Words
Henry Reaktion, Henry Nitroaldol Reaction, Nitro compounds
ID: J42-Y1997-160
