Organic Chemistry Portal

Abstracts

Search:

Calcium trifluoromethanesulfonate-catalysed aminolysis of epoxides

Ivica Cepanec*, Mladen Litvic, Hrvoje Mikuldas, Anamarija Bartolinicic and Vladimir Vinkovic

*Department for Development of Chemical Synthesis, BELUPO Pharmaceuticals and Cosmetics Ltd, Radnicka c. 224, 10000, Zagreb, Croatia, Email: ivica.cepanecbelupo.hr

I. Cepanec, M. Litvic, H. Mikuldas, A. Bartolincic, V. Vinkovic, Tetrahedron, 2003, 59, 2435-2439.

DOI: 10.1016/S0040-4020(03)00292-8


Abstract

A mild, calcium trifluoromethanesulfonate-catalyzed aminolysis of epoxides is very efficient in the synthesis of various β-amino alcohols with high regio- and stereoselectivity.


see article for more examples



Key Words

calcium trifluoromethanesulfonate, aminolysis, epoxides, β-amino alcohols


ID: J72-Y2003-390