Catalysis by an ionic liquid: efficient conjugate addition of thiols to electron deficient alkenes catalyzed by molten tetrabutylammonium bromide under solvent-free conditions
Brindaban C. Ranu*, Suvendu S. Dey and Alakananda Hajra
*Department of Organic Chemistry, Indian Association for the Cultivation of
Science, Jadavpur, Calcutta 700032, India, Email: ocbcr
iacs.res.in
B. C. Ranu, S. S. Dey, A. Hajra, Tetrahedron, 2003, 59, 2325-2331.
DOI: 10.1016/S0040-4020(03)00289-8
Abstract
Tetrabutylammonium bromide is an inexpensive ionic liquid, which efficiently catalyzes the conjugate addition of thiols to α,β-unsaturated nitriles, carboxylic esters, ketones and aldehydes as well as nitro olefins.
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Key Words
thiol, alkene, tetrabutylammonium bromide, conjugate addition, solvent-free reaction, ionic liquids
ID: J72-Y2003-500
