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A reductive amination of carbonyls with amines using decaborane in methanol

Jong Woo Bae, Seung Hwan Lee, Young Jin Cho, Cheol Min Yoon*

*Department of Life Science & Biotechnology, Graduate school of Biotechnology, Korea University, 1, 5-Ka, Anam-Dong Sungbuk-Ku, Seoul, 136-701 Korea, Email: cmyoonkorea.ac.kr

J. W. Bae, S. H. Lee, Y. J. Cho, C. M. Yoon, J. Chem. Soc., Perkin Trans. 1, 2000, 145-146.

DOI: 10.1039/a909506c


Abstract

Aldehydes and ketones were easily converted to the corresponding amines by the reaction of amines in methanol using decaborane (B10H14) at room temperature under nitrogen. The reaction is simple and efficient.

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A one-pot synthesis of N-alkylaminobenzenes from nitroaromatics: reduction followed by reductive amination using B10H14

J. W. Bae, Y. J. Cho, S. H. Lee, C.-O. M. Yoon, C. M. Yoon, Chem. Commun., 2000, 1857-1858.

Reductive Etherification of Aromatic Aldehydes with Decaborane

S. H. Lee, Y. J. Park, C. M. Yoon, Tetrahedron Lett., 1999, 40, 6049-6050.


Key Words

reductive amination, decaborane


ID: JXX-Y2000-370