A reductive amination of carbonyls with amines using decaborane in methanol

Jong Woo Bae, Seung Hwan Lee, Young Jin Cho, Cheol Min Yoon*

*Department of Life Science & Biotechnology, Graduate school of Biotechnology, Korea University, 1, 5-Ka, Anam-Dong Sungbuk-Ku, Seoul, 136-701 Korea, Email: cmyoonkorea.ac.kr

J. W. Bae, S. H. Lee, Y. J. Cho, C. M. Yoon, J. Chem. Soc., Perkin Trans. 1, 2000, 145-146.

DOI: 10.39/a909506c

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Abstract

Aldehydes and ketones were easily converted to the corresponding amines by the reaction of amines in methanol using decaborane (B₁₀H₁₄) at room temperature under nitrogen. The reaction is simple and efficient.

see article for more examples

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A one-pot synthesis of N-alkylaminobenzenes from nitroaromatics: reduction followed by reductive amination using B₁₀H₁₄

J. W. Bae, Y. J. Cho, S. H. Lee, C.-O. M. Yoon, C. M. Yoon, Chem. Commun., 2000, 1857-1858.

Reductive Etherification of Aromatic Aldehydes with Decaborane

S. H. Lee, Y. J. Park, C. M. Yoon, Tetrahedron Lett., 1999, 40, 6049-6050.

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Key Words

reductive amination, decaborane

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ID: JXX-Y2000-370