Ligand- and Base-Free Copper(II)-Catalyzed C-N Bond Formation: Cross-Coupling Reactions of Organoboron Compounds with Aliphatic Amines and Anilines
Tan D. Quach and Robert A. Batey*
*Davenport Research Laboratories, Department of Chemistry, University of
Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada, Email:
rbatey
chem.utoronto.ca
T. D. Quach, R. A. Batey, Org. Lett., 2003, 5, 4397-4400.
DOI: 10.1021/ol035681s
Abstract
A ligandless and base-free cross-coupling of arylboronic acids and potassium aryltrifluoroborate salts with primary and secondary aliphatic amines and anilines utilizes catalytic copper(II) acetate monohydrate and molecular sieves in dichloromethane at slightly elevated temperatures under an atmosphere of oxygen and tolerates a broad range of functional groups.
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Key Words
ID: J54-Y2003-1100
