Rhodium-Catalyzed Tandem Cyclization: Formation of 1H-Indenes and 1-Alkylideneindans from Arylboronate Esters in Aqueous Media
Mark Lautens* and Tzvetelina Marquardt
*Davenport Chemical Laboratories, Department of Chemistry, University of
Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada, Email:
mlautens
chem.utoronto.ca
M. Lautens, T. Marquardt, J. Org. Chem., 2004, 69, 4607-4614.
DOI: 10.1021/jo049722p (free Supporting Information)
Abstract
Arylboronate esters bearing a pendant Michael-type acceptor olefin undergo a transmetalation with a rhodium-based catalytic complex. These organorhodium intermediates can cyclize onto nonterminal acetylenes in good to excellent yields.
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Key Words
Rhodium, Catalysis, Indenes
ID: J42-Y2004-580
