Asymmetric Synthesis of Diarylmethyl Amines by Rhodium-Catalyzed Asymmetric Addition of Aryl Titanium Reagents to Imines
Tamio Hayashi*, Masahiro Kawai and Norihito Tokunaga
*Department of Chemistry, Graduate School of Science, Kyoto University,
Sakyo, Kyoto 606-8502, Japan, Email: thayashi
kuchem.kyoto-u.ac.jp
T. Hayashi, M. Kawai, N. Tokunaga, Angew. Chem., 2004, 116, 6251-6252.
DOI: 10.1002/ange.200461338 (free Supporting Information), DOI: 10.1002/anie.200461338 (International Edition)
Abstract
The asymmetric synthesis of diarylmethyl amines was realized by rhodium-catalyzed asymmetric addition of aryl titanium reagents to N-alkylidene sulfonamides.
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Key Words
amines, arylation, asymmetric catalysis, rhodium, titanium, diarylmethylamines
ID: J06-Y2004-870
