Organic Chemistry Portal

Abstracts

Search:

A Highly Effective (Triphenyl phosphite)palladium Catalyst for a Cross-Coupling Reaction of Allylic Alcohols with Organoboronic Acids

Yoshihito Kayaki, Takashi Koda, Takao Ikariya*

*Graduate School of Science and Engineering and Frontier Collaborative Research Center, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo, 152-8552, Japan, Email: tikariyaapc.titech.ac.jp

Y. Kayaki, T. Koda, T. Ikariya, Eur. J. Org. Chem., 2004, 4989-4993.

DOI: 10.1002/ejoc.200400621


see article for more reactions

Abstract

The cross-coupling reaction of aryl and vinyl boronic acids and allylic alcohols proceeded smoothly in toluene or dioxane in the presence of a (triphenyl phosphite)palladium catalyst to give the corresponding allylbenzene derivatives and 1,4-dienes. Neither cocatalysts for promoting C-O bond cleavage of allylic alcohols nor bases for activation of organoboron reagents are required.

see article for more examples



Key Words

Allylation, Boranes, C-C coupling, Green chemistry, Palladium


ID: J24-Y2004-930