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Pd(0)-Catalyzed Highly Selective Synthesis of 1,1-Diarylpropadienes and 1,3-Diarylpropynes from 1-Aryl-1-propynes and Aryl Halides

Shengming Ma,* Qiwen He and Xiuhui Zhang

*State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China, Email:

S. Ma, Q. He, X. Zhang, J. Org. Chem., 2005, 70, 3336-3338.

DOI: 10.1021/jo050183d (free Supporting Information)


1,1-diarylpropadienes and 1,3-diarylpropynes can be prepared respectively by the sequential lithiation of 1-aryl-1-propynes, transmetalation, and the corresponding Pd(0)-catalyzed cross-coupling with aryl halides under different reaction conditions.

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Key Words

Negishi Coupling, Allenes, Alkynylation, Arylmethanes

ID: J42-Y2005-420