Simple (Imidazol-2-ylidene)-Pd-Acetate Complexes as Effective Precatalysts for Sterically Hindered Suzuki-Miyaura Couplings
Rohit Singh, Mihai S. Viciu, Natalia Kramareva, Oscar Navarro and Steven P. Nolan*
*School of Chemistry, University of St Andrews, St Andrews
KY16 9ST, U.K., Email: sn17
st-andrews.ac.uk
R. Singh, M. S. Viciu, N. Kramareva, O. Navarro, S. P. Nolan, Org. Lett., 2005, 7, 1829-1832.
DOI: 10.1021/ol050472o
Abstract
Coupling of sterically hindered aryl and activated alkyl chlorides bearing β-hydrogens has been successfully achieved by using N-heterocyclic carbene (NHC)Pd-carboxylate complexes as catalysts.
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Key Words
Suzuki Coupling, Biaryls, Benzylation, Allylation
ID: J54-Y2005-430
