Hydroamination/Hydrosilylation Sequence Catalyzed by Titanium Complexes
Andreas Heutling, Frauke Pohlki, Igor Bytschkov, Sven Doye*
*Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im
Neuenheimer Feld 270, 69120 Heidelberg, Germany, Email:
sven.doye
urz.uni-heidelberg.de
A. Heutling, F. Pohlki, I. Bytschkov, S. Doye, Angew. Chem., 2005, 117, 3011-3013.
DOI: 10.1002/ange.200462250 (free Supporting Information), DOI: 10.1002/anie.200462250 (International Edition)
see article for more reactions
Abstract
The sequential combination of Ti-catalyzed hydroamination of alkynes followed by the Ti-catalyzed hydrosilylation of the intermediate imines is an efficient one-pot process for the conversion of alkynes and primary amines into secondary amines.
see article for more examples
Key Words
alkynes, amines, hydroamination, hydrosilylation, titanium, phenylsilane
ID: J06-Y2005-510
