Stereoselective Synthesis of (E)-β-Arylvinyl Bromides by Microwave-Induced Hunsdiecker-Type Reaction
Chunxiang Kuang*, Qing Yang, Hisanori Senboku, Masao Tokuda
*Department of Materials Chemistry, Graduate School of Engineering, Osaka University, Suita 565-0871, Japan, Email: kuangch.wani.osaka-u.ac.jp
C. Kuang, Q. Yang, H. Senboku, M. Tokuda, Synthesis, 2005, 1319-1325.
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(E)-β-Arylvinyl bromides were readily prepared in a short reaction time (1-2 min) by microwave irradiation of the corresponding 3-arylpropenoic acids in the presence of N-bromosuccinimide and a catalytic amount of lithium acetate.
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C. Kuang, H. Senboku, M. Tokuda, Tetrahedron, 2005, 61, 637-642.