Chiral Phosphine-Olefin Bidentate Ligands in Asymmetric Catalysis: Rhodium-Catalyzed Asymmetric 1,4-Addition of Aryl Boronic Acids to Maleimides
Ryo Shintani, Wei-Liang Duan, Takashi Nagano, Atsushi Okada, Tamio Hayashi*
*Department of Chemistry, Graduate School of Science, Kyoto University,
Sakyo, Kyoto 606-8502, Japan, Email: thayashi
kuchem.kyoto-u.ac.jp
R. Shintani, W.-L. Duan, T. Nagano, A. Okada, T. Hayashi, Angew. Chem., 2005, 117, 4687-4690.
DOI: 10.1002/ange.200501305 (free Supporting Information), DOI: 10.1002/anie.200501305 (International Edition)
Abstract
Novel chiral phosphine-olefin ligands have been designed, which acts as bidentate in an efficient rhodium-catalyzed asymmetric 1,4-addition of aryl boronic acids to maleimides.
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Key Words
alkenes, asymmetric catalysis, boron, P ligands, rhodium, conjugate addition
ID: J06-Y2005-1030
