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Highly Chemoselective Addition of Amines to Epoxides in Water

Najmodin Azizi and Mohammad R. Saidi*

*Department of Chemistry, Sharif University of Technology, P.O. Box 11465-9516, Tehran, Iran, Email:

N. Azizi, M. R. Saidi, Org. Lett., 2005, 7, 3649-3651.

DOI: 10.1021/ol051220q (free Supporting Information)


The mild aminolysis of a variety of epoxides in water gave β-amino alcohols with high selectivity and in excellent yields in the absence of any catalyst.

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Key Words

β-amino alcohols

ID: J54-Y2005-1080