Catalytic Asymmetric Synthesis with Rh-Diene Complexes: 1,4-Addition of Arylboronic Acids to Unsaturated Esters
Jean-François Paquin, Corey R. J. Stephenson, Christian Defieber and Erick M. Carreira*
*Laboratorium für Organische Chemie, ETH Hönggerberg, HCI H335, 8093 Zürich,
Switzerland, Email: carreira
org.chem.ethz.ch
J.-F. Paquin, C. R. J. Stephenson, C. Defieber, E. M. Carreira, Org. Lett., 2005, 7, 3821-3824.
DOI: 10.1021/ol051533l
Abstract
Various enantioenriched tert-butyl 3,3-diarylpropanoates are prepared via an asymmetric rhodium-catalyzed conjugate addition of arylboronic acids to unsaturated tert-butyl esters in the presence of chiral dienes as ligands.
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Key Words
ID: J54-Y2005-1220
