Nonreductive Deiodination of ortho-Iodo-Hydroxylated Arenes Using Tertiary Amines
Rahul Subhash Talekar, Grace Shiahuy Chen, Shin-Yu Lai and Ji-Wang Chern*
*School of Pharmacy, College of Medicine, National Taiwan University, No. 1,
Section 1, Jen-Ai Road, Taipei, Taiwan, ROC, Email: chern
jwc.mc.ntu.edu.tw
R. S. Talekar, G. S. Chen, S.-Y. Lai, J.-W. Chern, J. Org. Chem., 2005, 70, 8590-8593.
DOI: 10.1021/jo051191x
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Abstract
A mild, convenient, fast, and nonreductive deiodination is reported for ortho-iodo-hydroxylated arenes using pyridine, triethylamine, and N-methylmorpholine in the presence of water. The regioselectivity is discussed.
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proposed mechanism
Key Words
ID: J42-Y2005-1560
