Categories: Organic Chemistry

Advanced Organic Chemistry

Description

A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Editorial Review

Organic chemistry textbooks are generally aimed either at beginners or more advanced students. However, Reinhard Brückner’s “Advanced Organic Chemistry” is a work that can accommodate either undergraduate or graduate students.

The chapters are organized thematically, and contain sections that are targeted at both novice as well as more experienced students. The student working toward a first degree in chemistry can postpone study of those sections that are identified as advanced work, while the student pursuing an advanced degree can work through the entire text.

With its focus on reaction mechanisms, the Brückner text serves as an illustrative supplement to conventional textbooks, while it cannot replace them. The strengths of "Advanced Organic Chemistry" clearly lie in its very good explanations of mechanisms, the cleverly chosen examples (Brückner employs significantly fewer R-groups than other authors), and the literature citations for further reading.

For some of the mechanisms, such as S_N1 and S_N2, the examples are tabulated so that it is easy to recognize which is the relevant mechanism. The style of "Advanced Organic Chemistry" is generally engaging, and leads to a ready understanding, even of problematic chemical relationships.

Brückner is recommended as the resource to turn to when a supplementary treatment is needed.

Contents

Radical Substitution Reactions at the Saturated C Atom
Nucleophilic Substitution Reactions at the Saturated C Atom
Additions to the Olefinic C=C Double Bond
Eliminations
Substitution Reactions on Aromatic Compounds
Nucleophilic Substitution Reactions (Except Through Enolates) on the Carboxyl Carbon
Additions of Heteroatom Nucleophiles to Heterocumulenes
Additions of Heteroatom Nucleophiles to Carbonyl Compounds and Their Secondary Reactions
Addition of H Nucleophiles and Metal Organyls to Carbonyl Compounds
Reaction of Ylides with Saturated or Unsaturated Carbonyl Compounds
Chemistry of the Alkaline Earth Metal Enolates
Rearrangements
Thermal Cycloadditions
Transition Metal-Mediated Alkenylations, Arylations and Alkynylations
Oxidations and Reductions