Categories: Organic Chemistry >> Organometallics >> Transition Metals

Metal-Catalyzed Cross-Coupling Reactions

Description

This second, completely revised and expanded edition in two volumes comprehensively covers everything of importance related to C-C and C-N cross-coupling reactions. Internationally renowned experts present the current level of knowledge, while critical analyses and experiment guidelines allow users to quickly decide on strategies for solving their synthesis problems.

Editorial Review

Anyone who already has the first edition of "Metal-Catalyzed Cross-Coupling Reactions" will be truly amazed by the second edition. The book covers several additional reactions and synthesis concepts, and has been thoroughly revised. For this second edition, which could really be considered a completely new work, the editors have succeeded in getting the most acknowledged experts in the field, and in setting rather high standards of quality.

The latest mechanistic findings are discussed in detail, and new catalysts and reaction conditions are introduced. Some authors have given attention to examples of applications for particular cross-couplings, or have even described newly developed synthetic methods for several Main Group organometallics (e.g. boron, zinc and magnesium compounds) that are used as reaction partners in these coupling reactions. Thus, the reader obtains an extensive overview of the current developments in the area. An impressive finale is provided for most of the chapters in the form of a section on synthesis examples; indeed, it is regrettable that this feature is absent in a few of the chapters.

This tome is a great pleasure to read, offers the newest findings, and introduces a rich palette of options for chemists to exploit in their own experimental work. "Metal-Catalyzed Cross-Coupling Reactions" is a state of the art resource that can be recommended without reservation.

Contents

Mechanistic Aspects of Metal-Catalyzed C,C- and C,X-Bond Forming Reactions
Metal-Catalyzed Cross-Coupling Reactions of Organoboron Compounds
Organotin Reagents in Cross-Coupling
Organosilicon Compounds in Cross-Coupling Reactions
Cross-Coupling of Organyl Halides with Alkenes - The Heck Reaction
Cross-Coupling Reactions to sp Carbon Atoms
Carbometallation Reactions
Palladium-Catalyzed 1,4-Additions to Conjugated Dienes
Cross-Coupling Reactions via pi-Allyl Intermediates
Palladium-Catalyzed Coupling Reactions of Propargylic Compounds
Carbon-Carbon Bond Forming Reactions Mediated by Organozinc Reagents
Palladium-Catalyzed Aromatic Carbon-Nitrogen Bond Formation
The Directed ortho-Metalation Cross-Coupling Nexus
Palladium- or Nickel-Catalyzed Cross-Couling with Organometals Containing Zinc, Aluminium, and Zirconium