Carbon Tetrabromide, Tetrabromomethane, CBr4
Name Reactions
Recent Literature
A facile synthesis of aryl carboxylic acids from aryl ketones by aerobic
photooxidation using the inexpensive and easily handled CBr4 as
catalyst is applicable to inert compounds under usual photo-irradiation
conditions, and appears very attractive for the expansion of the Norrish Type I
reaction.
S.-i. Hirashima, T. Nobuta, N. Tada, A. Itoh, Synlett, 2009,
2017-2019.
The presence of catalytic amounts of carbon tetrabromide enables an aerobic
photooxidative cleavage of carbon-carbon triple bonds to carboxylic acids under
photoirradiation.
T. Yamaguchi, T. Nobuta, Y. Kudo, S.-i. Hirashima, N. Tada, T. Miura, A. Itoh, Synlett, 2013, 24,
607-610.
A base-promoted dibromination of enamides using CBr4 as a bromine
source provides β,β-dibrominated secondary enamides. These novel products can be
readily transformed to 5-Br oxazoles via Cu(I) catalyzed intramolecular
cyclization in good yields.
J. Ma, Q. Zou, C. Wang, G. Yin, F. Li, J. Org. Chem., 2022, 87,
15670-15678.
A carbon tetrabromide mediated oxidative carbon-nitrogen bond formation of
2-aminopyridines or 2-aminopyrimidines with β-keto esters or 1,3-diones provides
substituted imidazo[1,2-α]pyridines or imidazo[1,2-α]pyrimidines under mild and
metal-free conditions.
C. Huo, J. Tang, H. Xie, Y. Wang, J. Dong, Org. Lett., 2016, 18,
1016-1019.
