1,3-Diiodo-5,5-Dimethylhydantoin, DIH

DIH has a comparable reactivity to molecular iodine, but DIH is more convenient to handle, because the solid reagent does not sublimate. DIH is also an alternative to NIS (N-iodosuccinimide) for the iodination of arenes or enols.

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Recent Literature

Various primary alcohols, and primary, secondary, and tertiary amines were efficiently converted into the corresponding nitriles in good yields by oxidation with 1,3-diiodo-5,5-dimethylhydantoin (DIH) in aqueous ammonia at 60 °C.
S. Iida, H. Togo, Synlett, 2007, 407-410.

S. Iida, H. Togo, Synlett, 2007, 407-410.