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Chemicals >> Oxidizing Agents

Methyltrioxorhenium (MTO)

Methyltrioxorhenium is commercial available and stable in air. MTO is an exceptionally versatile oxygen transfer catalyst with hydrogen peroxide as terminal oxidant. A drawback is the limited stability in water.


Recent Literature


A convenient and efficient oxidation of hydroxylated and methoxylated benzaldehydes and acetophenones to the corresponding phenols uses hydrogen peroxide and methyltrioxorhenium as catalyst in ionic liquids [bmim]BF4 and [bmim]PF6.
R. Bernini, A. Coratti, G. Provenzano, G. Fabrizi, D. Tofani, Tetrahedron, 2005, 61, 1821-1825.


Homoallylic alcohols were efficiently epoxidized to the corresponding 3,4-epoxy alcohols in excellent yields in the presence of methyltrioxorhenium (MTO) as catalyst, aqueous hydrogen peroxide as the terminal oxidant, and 3-methylpyrazole as an additive. Organic solvent-free conditions accelerate the reaction.
S. Yamazaki, J. Org. Chem., 2012, 77, 9884-9888.


Sodium percarbonate is an ideal and efficient oxygen source for the oxidation of tertiary nitrogen compounds to N-oxides in excellent yields in the presence of various rhenium-based catalysts under mild reaction conditions.
S. L. Jain, J. K. Joseph, B. Sain, Synlett, 2006, 2661-2663.


Sodium percarbonate is an ideal and efficient oxygen source for the oxidation of tertiary nitrogen compounds to N-oxides in excellent yields in the presence of various rhenium-based catalysts under mild reaction conditions.
S. L. Jain, J. K. Joseph, B. Sain, Synlett, 2006, 2661-2663.


A general, high yielding, and user and environmentally friendly catalytic oxidation procedure for the chemoselective conversion of imines to nitrones is reported.
G. Soldaini, F. Cardona, A. Goti, Org. Lett., 2007, 9, 473-476.