Peroxy Acids
Examples: meta-Chloroperbenzoic acid, Peracetic Acid, Trifluoroacetic peracid
Sodium percarbonate allows the convenient preparation of peroxy acids from acid chlorides, and even from the acids themselves.
Recent Literature
Anhydrous [2-percarboxyethyl] functionalized silica is an advantageous
oxidant for epoxidation of olefins. The acidic silica surface does not catalyze
ring-opening reactions except for particularly activated styrene oxide. Alkenes
carrying hydroxyl groups react with silica-supported peracid faster than
unsubstituted alkenes. Products can be isolated after simple filtration and
solvent evaporation.
R. Mello, A. Alcalde-Aragonés, M. E. González Núńez, G. Asensio, J. Org. Chem., 2012,
77, 6409-6413.
The oxidation of malononitrile derivatives with peracid in methanol proceeds
with loss of the cyano groups to yield methyl esters in high yield. The method
was applied to a variety of malononitrile derivatives, some of which were
prepared by Pd- or Ir-catalyzed asymmetric allylic substitution.
S. Förster, O. Tverskoy, G. Helmchen, Synlett, 2008,
2803-2806.
