Sodium peroxydisulfate
See also: ammonium peroxydisulfate, choline peroxydisulfate, potassium peroxydisulfate, tetrabutylammonium peroxydisulfate
Recent Literature
A silver-catalyzed double-decarboxylative protocol enables an efficient and
pratical construction of chalcone derivatives via cascade coupling of
substituted α-keto acids with cinnamic acids under mild and environmentally
benign aqueous conditions.
N. Zhang, D. Yang, W. Wei, L. Yuan, F. Nie, L. Tian, H. Wang, J. Org. Chem.,
2015,
80, 3258-3263.
An efficient Na2S2O8-promoted radical coupling
of tertiary cycloalkanols with alkynyl hypervalent iodide reagents provides β-,
γ- and δ-alkynylated ketones via C-C bond cleavage. This tandem ring-opening/alkynylation
procedure offers mild conditions and wide substrate scope.
S. Wang, L.-N. Guo, H. Wang, X.-H. Duan, Org. Lett.,
2015,
17, 4798-4801.
In a copper-free Sandmeyer-type fluorosulfonylation reaction with Na2S2O5
as the sulfur dioxide source and Selectfluor as fluorine source, aryldiazonium
salts are transformed into sulfonyl fluorides. In situ diazotization enables the
use of aromatic amines as substrates. The method offers broad functional group
tolerance, gram-scale synthesis and late-stage fluorosulfonylation.
T. Zhong, M.-K. Pang, Z.-D. Chen, B. Zhang, J. Weng, G. Lu,
Org. Lett., 2020, 22, 2941-2945.
Iodofluorination of aliphatic and aromatic alkenes with iodine and
HF·pyridine complex (pyr·9HF) was performed under mild conditions in the
presence of K2S2O8 or Na2S2O8
as oxidants. Substitution reactions of the iodofluorinated products by nitrogen,
sulfur, and oxygen nucleophiles enable further applications as a building blocks
for synthesis of 2-fluoroalkyl-substituted compounds.
T. Kitamura, R. Komoto, J. Oyamada, M. Higashi, Y. Kishikawa, J. Org. Chem., 2021, 86,
18300-18303.
A Pd-catalyzed C-H bond activation/C-C bond formation/cyclization cascade
process enables the synthesis of quinolinone derivatives from simple anilines as
the substrates. This method provides access to quinolinone-containing alkaloids
and drug molecules.
J. Wu, S. Xiang, J. Zeng, M. Leow, X.-W. Liu, Org. Lett.,
2015,
17, 222-225.
A transition-metal-free alkylation and acylation of C(sp2)-H bonds
in biologically relevant 2-benzoxazinones with 1,4-dihydropyridines offers
excellent functional group compatibility and a broad substrate scope.
Y. Byun, J. Moon, W. An, N. K. Mishra, H. S. Kim, P. Ghosh, I. S. Kim, J. Org. Chem., 2021, 86,
12247-12256.
The use of vinyl ethers as robust, inexpensive acetyl sources enables a mild,
operationally simple Minisci C-H acetylation of N-heteroarenes. The
reaction does not require a catalyst or high temperature and is therefore
significantly more sustainable than previously reported methods in terms of cost,
reagent toxicity, and waste generation.
J. Dong, J. Liu, H. Song, Y. Liu, Q. Wang, Org. Lett., 2021, 23,
4374-4378.
The use of vinyl ethers as robust, inexpensive acetyl sources enables a mild,
operationally simple Minisci C-H acetylation of N-heteroarenes. The
reaction does not require a catalyst or high temperature and is therefore
significantly more sustainable than previously reported methods in terms of cost,
reagent toxicity, and waste generation.
J. Dong, J. Liu, H. Song, Y. Liu, Q. Wang, Org. Lett., 2021, 23,
4374-4378.
An iron-catalyzed oxidative cyclization of 1-acyl-3-(phenyl)thioureas in the
presence of sodium persulfate gave various N-benzothiazol-2-yl-amides selectively in good yields
through C(sp2)-H functionalization and C-S bond formation.
J. Wang, Y. Zong, X. Zhang, Y. Gao, Z. Li, G. Yuo, Z. Quan, X. Wang,
Synlett, 2014, 25, 2143-2148.
