Trichloroisocyanuric Acid (TCCA)
Recent Literature
A highly convenient organocatalytic method for the mono-oxidation of
unprotected glycosides relies on the chemoselective properties of TEMPO in
combination with trichloroisocyanuric acid under very mild, basic conditions.
The resulting dialdo-glycosides are efficiently purified with the use of
solid-phase imine capture.
M. Angelin, M. Hermansson, H. Dong, O. Ramström, Eur. J. Org. Chem., 2006,
4323-4326.
An efficient one-pot conversion of various alcohols, aldehydes and primary
amines into the corresponding nitriles in excellent yields was easily achieved
by the use of trichloroisocyanuric acid (TCCA) as an oxidant in aqueous ammonia.
Also, various benzylic halides were smoothly and directly converted into the
corresponding aromatic nitriles in high yields under the same conditions.
H. Veisi, Synthesis, 2010,
2631-2635.
An efficient and highly selective method for the oxidative conversion of
primary amines to the corresponding nitriles using trichloroisocyanuric acid
in the presence of catalytic TEMPO provides a new entry to the synthesis of
various aliphatic, aromatic and heterocyclic nitriles in excellent yield.
F.-E. Chen, Y.-Y. Kuang, H.-F. Dai, L. Lu, M. Huo, Synthesis,
2003, 2629-2631.
