LAH, Lithium aluminum hydride, Lithium tetrahydridoaluminate
LiAlH4 is a very common, strong reducing agent, which reduces a vast number of different functional groups.
Recent Literature
The preparation of alkenyl halides of any length from inexpensive starting
reagents is reported. Standard organic transformations were used to prepare
straight-chain α-olefin halides in excellent overall yields with no
detectable olefin isomerization and full recovery of any unreacted starting
material.
T. W. Baughman, J. C. Sworen, K. B. Wagener, Tetrahedron, 2004, 60, 10943-10948.
Trifluoromethyl arenes were reduced with lithium aluminum hydride to give
toluene derivatives in good yields in the presence of 5 mol % of niobium(V)
chloride. Stepwise, partial reduction of a bis(trifluoromethyl) arene was
also demonstrated.
K. Fuchibe, Y. Ohshima, K. Mitomi, T. Akiyama, Org. Lett., 2007,
9, 1497-1499.
