Further Information
Literature
Related Reactions
Dess-Martin Oxidation
Jones Oxidation
Swern Oxidation
Corey-Kim Oxidation
The Corey-Kim Oxidation allows the synthesis of aldehydes and ketones from primary alcohols and secondary alcohols, respectively.
Mechanism of the Corey-Kim Oxidation
Dimethylchlorosulphonium ion is generated in situ from NCS and DMS:
The following steps are comparable to the Swern Oxidation:
Recent Literature
New odorless method for the Corey–Kim and Swern oxidations utilizing dodecyl
methyl sulfide (Dod-S-Me)
S.-I. Ohsugia, K. Nishidea, K. Oonob, K. Okuyamab, M.
Fudesakaa, S. Kodamaa, M. Node, Tetrahedron, 2003, 59, 8393-8398.
The fluorous Swern and Corey-Kim reaction: scope and mechanism
D. Crich, S. Neelamkavil, Tetrahedron, 2002, 58, 3865-3870.