Organic Chemistry Portal
Reactions >> Name Reactions

Further Information

Related Reactions
Cope Elimination
Ester Pyrolysis
Hofmann's Rule

Hofmann Elimination

Sometimes referred to as the Hofmann Degradation. This elimination reaction of alkyl trimethyl amines proceeds with anti-stereochemistry, and is generally suitable for producing alkenes with one or two substituents. The reaction follows the Hofmann Rule.

Mechanism of the Hofmann Elimination