Categories: C-B Bond Formation >
Synthesis of boranes
Name Reactions
Recent Literature
An efficient method of constructing 4-benzyl piperidines and related
substances is described. This protocol tolerates a wide variation in both
reaction partners and allows the concise formation of a variety of building
blocks.
S. Vice, T. Bara, A. Bauer, C. A. Evans, J. Fort, H. Josien, S. McCombie, M.
Miller, D. Nazzareno, A. Palani, J. Tagat, J. Org. Chem,
2001,
66, 2487-2492.
Various N-acylethylenediamine-based ligands were screened as
catalysts for the asymmetric addition of vinylzinc reagents to aldehydes.
The optimized ligand was found to catalyze the formation of (E)-allylic
alcohols with high enantioselectivities for both aromatic and α-branched
aldehydes, and vinylzinc reagents derived from both bulky and straight chain
terminal alkynes.
C. M. Sprout, M. L. Richmond, C. T. Seto, J. Org. Chem., 2005,
70, 7408-7417.
