Categories: C-C Bond Formation > Chains >
Synthesis of 1,3-dienes
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Recent Literature

An efficient method for the preparation of various
2-aminomethyl-1,3-dienes was developed through the reaction of imines with an
organoindium reagent generated in situ from indium and 1,3-dibromo-2-butyne.
Three-component reactions of aldehydes, amines, and organoindium reagents gave
successful results in a one-pot process.
D. Seomoon, J. A, P. H. Lee, Org. Lett., 2009,
11, 2401-2404.
