Categories: C-I Bond Formation >
Synthesis of 1,2-iodoamines
Recent Literature

An efficient and mild thiophenol-promoted ring-opening of aziridines or epoxides
with iodine afforded β-iodo amines or β-iodo alcohols in very good yields.
J. Wu, X. Sun, W. Sun, S. Ye, Synlett, 2006,
2489-2491.

Aziridines are opened regioselectively with hydrogen and lithium halides to
yield β-haloamines in the presence of β-cyclodextrin using water as the solvent.
N. S. Krishnaveni, K. Surendra, M. Narender, Y. V. D. Nageswar, K. R. Rao, Synthesis, 2004,
501-502.
