Categories: C-N Bond Formation > Synthesis of amides >
Synthesis of amides by rearrangements or hydrolysis
Name Reactions
Recent Literature
A wide range of aldoximes has been converted into the corresponding amides in
high yield and selectivity using the ruthenium-based catalyst Ru(PPh3)3(CO)H2/dppe/TsOH
with catalyst loading as low as 0.04 mol%.
N. A. Owston, A. J. Parker, J. M. J. Williams, Org. Lett., 2007,
9, 3599-3601.
[Ir(Cp*)Cl2]2 catalyzes the rearrangement of oximes to
furnish amides. An iridium-catalyzed transfer
hydrogenation between alcohols and styrene and the subsequent formation of an
oxime allows the conversion of alcohols
into amides in a one-pot process.
N. A. Owston, A. J. Parker, J. M. J. Williams, Org. Lett., 2007,
9, 73-75.
