Categories: C-N Bond Formation > Synthesis of amides >
Aminocarbonylation
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Recent Literature

A Pd-catalyzed aminocarbonylation of aryl bromides into the corresponding
Weinreb amides at atmospheric pressure efficiently transforms
eletron-deficient, - neutral, and -rich aryl bromides.
J. R. Martinelli, D. M. M. Freckmann, S. L. Buchwald, Org. Lett.,
2006,
8, 4795-4797.

Molybdenum hexacarbonyl is a convenient and solid carbon monoxide source in a microwave-accelerated palladium-catalyzed aminocarbonylation of aryl bromides and iodides.
16 different aromatic amides were synthesized under air in good yields after
only 15 min of controlled microwave irradiation.
J.
Wannberg, M. Larhed, J. Org. Chem., 2003, 68, 5750-5753
