Categories: C-N Bond Formation > Synthesis of azides >
Synthesis of 1,1-Diazides
Recent Literature
The reaction of 1,3-dicarbonyl compounds with molecular iodine and sodium azide
in aqueous DMSO provides a general access to a broad range of geminal diazides
with various structural motifs including sterically demanding substituents and
ordinary functional groups. The diazidation of 1,3-dicarbonyls can be
selectively achieved even in the presence of other 1,3-dicarbonyls with
substituents at 2-position.
H. Erhardt, A. P. Häring, A. Kotthaus, M. Roggel, M. L. Tong, P. Biallas, M.
Jübermann, F. Mohr, S. F. Kirsch, J. Org. Chem.,
2015,
80, 12462-12469.