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Categories: C-N Bond Formation > Enamines

Synthesis of β-enamino esters

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β-Keto esters efficiently react with a variety of amines in the presence of 0.1 equivalents of acetic acid as an inexpensive and environmentally benign catalyst without any solvents under ultrasound to give good yields of the corresponding β-enamino esters.
C. A. Brandt, A. C. M. P. da Silva, C. G. Pancote, C. L. Brito, M. A. B. da Silveira, Synthesis, 2004, 1557-1558.