Categories: C-N Bond Formation > Enamines

Synthesis of ketene aminals

Recent Literature

A silver-based catalyst promotes a syn-selective hydroamination of electron-rich alkynes with either secondary amides or carbamates. This method is efficient for the synthesis of various synthetically useful silyl ketene aminals. The mechanism is discussed.
J. Sun, S. A. Kozmin, Angew. Chem. Int. Ed., 2006, 45, 4991-4993.