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Synthesis of sulfoximines

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A simple and mild copper salt-catalyzed N-arylation of sulfoximines with aryl boronic acids is reported. The cross-couplings proceed without additional base at room temperature.
C. Moessner, C. Bolm, Org. Lett., 2005, 7, 2667-2669.


Two simple, inexpensive, and mild methods for copper-catalyed N-arylations of sulfoximines with aryl bromides and aryl iodides provide various N-arylated sulfoximines in high yields. These methods help to avoid the use of palladium catalysts or stoichiometric quantities of copper salts.
J. Sedelmeier, C. Bolm, J. Org. Chem., 2005, 70, 6904-6906.


J. Sedelmeier, C. Bolm, J. Org. Chem., 2005, 70, 6904-6906.