Synthesis of carbamates by carbamoylation

Related:

Recent Literature

Readily prepared carbamoylimidazolium salts act as efficient N,N-disubstituted carbamoylating reagents, as a result of the ‘imidazolium’ effect. The salts react with amines, thiols, phenols/alcohols, and carboxylic acids in high yields, without the need for subsequent chromatographic purification of the products, producing ureas, thiocarbamates, carbamates, and amides, respectively.
M. B. Bertrand, J. P. Wolfe, Tetrahedron, 2005, 61, 6447-6459.

M. B. Bertrand, J. P. Wolfe, Tetrahedron, 2005, 61, 6447-6459.

The reaction of Grignard reagents with alkyl imidazolecarboxylates, which were prepared from alcohols with carbonyl diimidazole, gave the corresponding esters in good to excellent yields.
T. Werner, A. G. M. Barrett, J. Org. Chem., 2006, 71, 4302-4304.