Synthesis of hemiaminals and hemiaminal ethers

Recent Literature

An enantioselective addition of alcohols to imines proceeds in the presence of a catalytic amount of a chiral phosphoric acid catalyst to give the respective chiral N,O-aminals in excellent yield and enantioselectivity.
G. Li, F. R. Fronczek, J. C. Antilla, J. Am. Chem. Soc., 2008, 130, 12216-12217.