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Synthesis of α-hydroxy phosphonates

Recent Literature

A very convenient reaction of trialkyl phosphites with aldehydes or ketones in the presence of hydrogen chloride gives dialkyl 1-hydroxyalkylphosphonates in good yields via an Arbusov-like reaction of oxonium salts derived from aldehydes or ketones. This reaction is an alternative to the well-known Abramov reaction.
W. Goldeman, M. Soroka, Synthesis, 2006, 3019-3024.