Categories: C-S Bond Formation >
Synthesis of propargylic sulfides
Recent Literature
A general and efficient FeCl3-catalyzed substitution reaction of
propargylic alcohols with carbon- and heteroatom-centered nucleophiles such
as allyl trimethylsilane, alcohols, aromatic compounds, thiols, and amides,
forms new C-C, C-O, C-S and C-N bonds.
Z.-P. Zhan, J.-L. Yu, Y.-Y. Cui, R.-F. Yang, W.-Z. Yang, J.-P. Li, J. Org. Chem., 2006, 71, 8298-8301.
A ruthenium-catalyzed S-propargylation of thiols by propargylic carbonates
under neutral conditions, in which specific requirements inherent to the
different reactivities of aliphatic and aromatic thiols was achieved by
tuning both the nature of the ligands and the experimental conditions.
T. Kondo, Y. Kanda, A. Baba, K. Fukuda, A. Nakamura, K. Wada, Y. Morisaki,
T.-A. Mitsudo, J. Am. Chem. Soc., 2002, 124, 12960-12961.
T. Kondo, Y. Kanda, A. Baba, K. Fukuda, A. Nakamura, K. Wada, Y. Morisaki,
T.-A. Mitsudo, J. Am. Chem. Soc., 2002, 124, 12960-12961.
