Categories: C-S Bond Formation > Synthesis of sulfones >
Synthesis of allylic sulfones
Recent Literature
Formation of allyl phenyl sulfones with excellent yields from allylic alcohols
was promoted by a combination of Pd(OAc)2, PPh3, and
Et3B via in situ activation of the alcohol group.
S. Chandrasekhar, V. Jagadeshwar, B. Saritha, C. Narsihmulu, J. Org. Chem., 2005, 70, 6506-6507.
A one-pot synthesis of aryl sulfones from primary alcohols is described.
Alcohols were treated with N-bromosuccinimide and triphenylphosphine,
followed by addition of sodium arenesulfinate with a catalytic amount of
tetrabutylammonium iodide to afford the aryl sulfones in good to high yields.
T. Murakami, K. Furusawa, Synthesis, 2002, 479-482.
