Categories: C-S Bond Formation > Synthesis of sulfones >
Vinyl sulfones
Recent Literature
The palladium-catalyzed reaction of sulfinic acid salts with a wide variety
of aryl and vinyl halides or triflates, which is strongly influenced by the
presence of nBu4NCl, provides unsymmetrical diaryl
sulfones and aryl vinyl sulfones in good yields. The use of Xantphos, a
rigid bidentate ligand with a wide natural bite angle, was found to be
crucial for the success of the reaction.
S. Cacchi, G. Fabrizi, A. Goggiamani, L. M. Parisi, R. Bernini, J. Org.
Chem., 2004, 69, 5608-5614.
An efficient synthesis of vinyl sulfones with commercially available sulfinic acid sodium salts
and dibromides gave various phenyl and methyl vinyl sulfones in
good yields, in the absence of any catalyst.
Z.-H. Guan, W. Zuo, L.-B. Zhao, Z.-H. Ren, Y.-M. Liang, Synthesis, 2007,
1465-1470.
An efficient synthesis of vinyl sulfones with commercially available sulfinic acid sodium salts
and dibromides gave various phenyl and methyl vinyl sulfones in
good yields, in the absence of any catalyst.
Z.-H. Guan, W. Zuo, L.-B. Zhao, Z.-H. Ren, Y.-M. Liang, Synthesis, 2007,
1465-1470.
The cerium(IV) ammonium nitrate (CAN) mediated reaction of aryl sulfinates
and sodium iodide with alkenes afforded vinyl sulfones in very good yields.
Alkynes underwent a similar reaction to give β-iodovinyl sulfones, which on
treatment with potassium carbonate afforded the corresponding acetylenic
sulfones in high yields.
V. Nair, A. Augustine, T. D. Suja, Synthesis, 2002, 2259-2265.
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