Categories: C=C Bond Formation >
Synthesis of 1,3-enynes by olefination
| Related: |  |
Recent Literature
Deprotonation of 3,3,3-trichloropropyl-1-triphenylphosphonium chloride
generates the corresponding phosphorane, which reacts with aldehydes to give
trichloromethylated (Z)-olefins, which are useful for the synthesis
of (Z)-1,3-enynes, (Z,Z)-1-chloro-1,3-dienes, and 1,3-diynes
in high yields and stereospecificities.
M. S. Karatholuvhu, P. L. Fuchs, J. Am. Chem. Soc.,
2004, 126, 14314-14315.
