Categories: C=C Bond Formation >
Synthesis of nitro alkenes
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Recent Literature
By changing reaction conditions (solvent and temperature), it is possible to
control the stereochemical outcome of the condensation of aliphatic aldehydes
with nitro alkanes obtaining pure (E)- and (Z)-nitro alkenes in
high to excellent yields. The role of molecular sieves on the stereochemical
control seems crucial in addition to that of piperidine for the synthesis of the
Z isomer.
S. Fioravanti, L. Pellacani, P. A. Tardella, M. C. Vergari, Org. Lett., 2008,
10, 1449-1451.
S. Fioravanti, L. Pellacani, P. A. Tardella, M. C. Vergari, Org. Lett., 2008,
10, 1449-1451.
