Categories: C=N Bond Formation >
Synthesis of amidines
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Recent Literature
A highly efficient, mild, copper-catalyzed multicomponent reaction
for the synthesis of N-sulfonylamidines has been developed. This reaction has an
extremely wide scope with regard to all three coupling components of alkyne,
sulfonyl azide, and amine. Two plausible mechanistic pathways are discussed.
I. Bae, H. Han, S. Chang, J. Am. Chem. Soc.,
2005, 127, 2038-2039.
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